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16 days, Mexico City to Santiago De Cuba
Your holiday at a glance
Sixteen days across Mexico and Cuba. You sleep 3 nights in Mexico City, 1 night in Patzcuaro, 2 nights in Guadalajara, 1 night in Guanajuato and 6 more stops. The route also calls at Mine Two Star, Tlalpujahua, Morelia, Tlaquepaque and Dolores Hidalgo and 9 more. 10 UNESCO listed sights sit on the itinerary, among them Zócalo (Plaza de la Constitución) and Metropolitan Cathedral.
Travel is by coach with an English speaking guide, and hotels and breakfast are included, along with your arrival transfer.
The experience
Pick a day. See where you go, what you do and where you stay.
Welcome to Mexico! Upon arrival, we’ll provide a transfer to the hotel, after which you will have free time. Our guide will contact you late in the afternoon.
If you requested additional nights, your room will be ready upon arrival at the hotel, but your trip guide will only contact you when the included activities begin. Until then, you’ll have free time to enjoy at your leisure.
The schedules provided in this itinerary are indicative. The guide may adjust them as needed to enhance the trip experience.
Today we have a fantastic day ahead to explore Mexico.
In the morning, we’ll head to the neighborhood of Xochimilco, a wonderful place known for its canals and semi-floating gardens, where we’ll enjoy a ride on a “trajinera”, colorful boats decorated with flowers. Afterwards, we’ll take a panoramic tour of the city, visiting the Plaza of the Three Cultures, the historic downtown where we’ll see the Zócalo and its Metropolitan Cathedral, the Aztec Templo Mayor, Chapultepec Park, Paseo de la Reforma, and the main avenues of this impressive city. We’ll have free time for lunch at the Zócalo in Mexico City. After lunch, we’ll visit the Basilica of Guadalupe, the most visited Catholic shrine in the Americas, home to the Virgin of Guadalupe. There, we’ll see both the old 18th-century basilica and the modern temple.
Return to the hotel.
In the evening, we’ll head to Plaza Garibaldi (transfer included), famous for its many cantinas, restaurants, and bars where tacos and tequila are served and Mariachi bands fill the night with music.
Dinner is included at a typical Mexican restaurant, where we’ll toast with a tequila and enjoy traditional Mariachi songs.
Mexico City – Departure. We’ll leave the capital behind and head into the green landscapes of the State of Mexico. A mountain route will take us to our first destination.
Mina de las Dos Estrellas – Arrival. We’ll visit this fascinating site museum, located in a former gold mine, where we’ll learn about the lives of the miners and the technological advances of their time. Admission included.
Mina de las Dos Estrellas – Departure. We’ll continue our journey through mountain landscapes, temporary home of the monarch butterfly.
Tlalpujahua – Arrival.
This charming Pueblo Mágico in the state of Michoacán welcomes us with its year-round Christmas atmosphere, famous for its handcrafted blown-glass ornaments. The highlight here is the Sanctuary of Our Lady of Carmen, featuring a Baroque façade in pink stone. We’ll have time to enjoy lunch and stroll through the cobblestone streets, lined with shops displaying Santa Claus figures all year long.
Tlalpujahua – Departure. Our route will take us through mountains and Purépecha lands on the way to our final destination.
Pátzcuaro – Arrival.
We’ll take a panoramic tour of one of the most beautiful colonial cities in Mexico, where pre-Hispanic heritage blends with colonial architecture. Its tree-lined plazas, the lake that shares its name, and its craft markets give Pátzcuaro a truly unique atmosphere. You’ll have free time to start exploring this gem of the Michoacán highlands.
372 km Scenery: We’ll travel through the mountains of central Mexico, passing forested valleys filled with pines and oaks — a landscape where nature and mining history intertwine.
Pátzcuaro – Departure. We’ll leave this colonial gem behind and head toward one of the most important capitals in the country, passing through the characteristic landscapes of the Michoacán highlands.
Morelia – Arrival.
The capital of the state of Michoacán, Morelia is considered one of Mexico’s most beautiful cities for its impressive pink-stone architecture. Its historic center, declared a UNESCO World Heritage Site, is filled with majestic Baroque buildings and tree-lined plazas. Highlights include its Cathedral, with its tablerado Baroque style and twin towers over 60 meters high, the Plaza de Armas, and the University of Morelia, one of the oldest in the Americas, founded in 1540. There will be free time to stroll and enjoy lunch in one of its traditional restaurants or cafés.
Morelia – Departure. We’ll continue our journey toward Guadalajara, the capital of the state of Jalisco.
Tlaquepaque.
Before arriving in Guadalajara, we’ll stop in Tlaquepaque, one of the Pueblos Mágicos located near the city. Enjoy free time to wander through its charming streets filled with Mariachi music, live performances, artisan shops, and a wide variety of local cuisine.
Tlaquepaque – Departure.
Guadalajara – Arrival. We’ll arrive in one of Mexico’s most vibrant cities, the birthplace of Mariachi and Tequila. Its historic center blends colonial architecture, lively plazas, and a unique cultural atmosphere.
351 km Scenery: We’ll travel through the heart of western Mexico, crossing gentle hills, cultivated fields, and beautiful lakes, discovering towns rich in history and monumental cities.
In the morning, we’ll take a panoramic tour of Guadalajara, a city that blends modernity with deep-rooted traditions.
We’ll explore its elegant historic center and admire landmarks such as the Metropolitan Cathedral, Plaza Tapatía, the traditional San Juan de Dios Market, and the impressive Hospicio Cabañas (admission included), a UNESCO World Heritage Site housing murals by José Clemente Orozco.
Departure from Guadalajara. We’ll travel by road toward the picturesque town of Tequila, birthplace of one of Mexico’s most iconic beverages.
Tequila.
Arrival in this colorful town that preserves its traditional charm with cobbled streets, vibrant facades, and surrounding agave plantations. We’ll visit the renowned Mundo Cuervo distillery, where we’ll learn about the artisanal process of tequila production (admission and tasting included). After the visit, you’ll have time to explore the town, browse its local shops, and enjoy lunch at one of its traditional restaurants.
Departure from Tequila. We’ll begin our return journey to the Jalisco capital, once again enjoying the scenic agave landscape.
Guadalajara. Arrival with free time to continue exploring the city, do some shopping, or enjoy its lively nightlife.
We’ll journey through the fertile valleys of the state of Jalisco, with sweeping views of the blue agave fields—recognized as a UNESCO World Heritage Site for their cultural significance in tequila production.
Upon arrival in Tequila, the bus cannot enter the historic center; a walk of approximately 20 minutes will be required.
During high season, the distillery visit may be scheduled in the morning, in which case the order of visits will be adjusted without altering the planned content.
275 km 08:00 h.- Guadalajara –Departure-. 13:00 h.- GUANAJUATO – Arrival-.
It is forbidden by law the entry of tourist buses into the historic centre. On arrival, walk down to the Pípila viewpoint , time for photos. Afterwards, we will take the cable car ride to the centre. Free time to have lunch. After lunch, we will visit this beautiful university city declared World Heritage Site, its steep slopes, its narrow streets, its temples. We included a visit to this beautiful university city and World Heritage Site, with its narrow, steep streets and churches. Followed by free time. Visitors who are interested can visit the impressive “Mummies´ Museum”. 17.30/18.00 hrs: Transfer by sprinter vehicle to the hotel.
Departure from Guanajuato. We’ll enjoy stunning mountainous landscapes along the way.
Dolores Hidalgo. Known as the birthplace of Mexican independence, here you’ll have the opportunity to visit the church where Father Hidalgo issued the famous call for independence.
Departure from Dolores Hidalgo.
En route, we’ll visit the Sanctuary of Atotonilco, also known as the "Sanctuary of God and the Nation," a UNESCO World Heritage Site. (Please note: On some occasions, access to the interior may not be possible due to religious retreats.)
San Miguel de Allende. A beautiful city with colonial architecture and cobblestone streets, declared a UNESCO World Heritage Site. You’ll have time to stroll and explore its charming atmosphere.
Departure from San Miguel de Allende.
Queretaro. Arrival in this beautiful city, famous for its stunning colonial center, its lively Plaza de Armas, and its vibrant pedestrian streets and restaurants.
Beautiful mountain landscapes along the route between Guanajuato and Dolores Hidalgo.
The city regulations prohibit tourist buses from entering the historic center.
The city regulations prohibit tourist buses from entering the historic center. In this case, the alternatives are a 15-minute walk or using a public transportation minibus. Please note that the quality of this public transport may be lower than desired.
Querétaro – Departure. We’ll begin our route heading south, entering regions rich in history and culture.
Tula – Arrival.
We’ll visit the archaeological site of Tula ( entrance included ), the ancient capital of the Toltecs, a civilization that laid the foundations for many Mesoamerican traditions. Among its most impressive structures are the Atlantes, massive four-meter-tall warrior statues carved in stone — symbols of Toltec military power. You’ll also see remains of pyramids, palaces, and intricately carved columns that showcase the sophistication of this culture.
Tula – Departure. We’ll continue by road toward one of Mexico’s most emblematic colonial cities.
Puebla – Arrival.
We’ll take a panoramic tour of this UNESCO World Heritage city, famous for its exquisite cuisine (the birthplace of mole poblano ), Baroque colonial architecture, and Talavera ceramics. Highlights include its magnificent Renaissance-style cathedral, one of the most impressive in the Americas, and its vibrant Zócalo, a lively meeting place surrounded by arcaded walkways. You’ll have free time to enjoy lunch and stroll through the historic center.
Puebla – Departure. We’ll continue our journey toward Mexico City.
Mexico City – Arrival.
471 km Scenery: We’ll travel across the central Mexican highlands, passing cultivated fields, mountain ranges, and volcanic landscapes. This journey offers the chance to experience ancient, colonial, and contemporary Mexico all in one day.
After breakfast a transfer takes you to the airport to take your flight to La Havana.
Upon arrival, we shall be waiting for you to transfer you to your hotel. To welcome you at the end of the afternoon we will include a trip in an old classic car to the fortress of San Carlos passing the ‘Malecón’ and we will attend the cannon shooting ceremony (admission included) . Return to the hotel (by coach or vehicles) and accommodation.
This morning, we’ll enjoy a tour lasting approximately four hours.
We’ll explore Colonial Havana, a UNESCO World Heritage Site, as well as Revolution Square and the University of Havana. We’ll also v isit the Havana Club Rum Museum . Later, we’ll cross the bay by boat to the town of Regla to visit the Church of the Virgin of Regla, a deeply spiritual place where Catholic and Afro-Cuban beliefs intertwine in a powerful display of religious syncretism. Will you buy flowers and have your palm read by a daughter of Ochún? Around lunchtime, we’ll head to the Callejón del Chorro area, known for its many paladares (privately owned restaurants), where you’ll have time to stroll and enjoy lunch. Free time in the afternoon.
Departure from Havana. We’ll travel south across sugar cane fields, palm groves, and small towns, heading toward one of Cuba’s most biodiverse regions.
Guamá.
Located within the Zapata Swamp National Park, we’ll visit the Crocodile Breeding Center and take a boat ride on the Treasure Lagoon, surrounded by Taino legends and lush vegetation. In the nearby Taino Village, we’ll explore a re-creation of pre-Columbian life, featuring life-sized sculptures that depict the early Caribbean inhabitants.
Departure from Taino Village. We’ll continue along the Caribbean coastline to reach Punta Perdiz.
Punta Perdiz. Free time to enjoy the sea. Lunch will be included, and you’ll have the chance to swim, explore natural cenotes, or go snorkeling in the crystal-clear waters filled with marine life.
Departure from Punta Perdiz. We’ll continue our journey toward a place of great significance in Cuba’s recent history.
Playa Girón. Visit to the Playa Girón Museum, which tells the story of the Bay of Pigs invasion and the Cuban resistance during the revolution.
Departure from Playa Girón. We’ll take the road to our final destination for the day.
Cienfuegos. Known as “The Pearl of the South,” this elegant port city, with its French neoclassical architecture, will charm us as we tour the historic center, the seafront promenade, and Punta Gorda.
Departure from Cienfuegos toward the hotel.
Arrival at Rancho Luna Hotel. Dinner will be included and overnight stay.
This route will take us through lush Cuban tropical landscapes, mangroves, and protected wetlands. Later, we’ll drive along the Caribbean coast, where crystal-clear waters and rich vegetation create a stunning backdrop.
Wear comfortable clothing, a swimsuit, and non-slip shoes for water activities. Have your camera ready to capture the diverse flora and fauna of the national park.
Departure from Cienfuegos. We’ll leave behind this elegant colonial city and head toward Trinidad, a heritage jewel nestled between the Escambray Mountains and the Caribbean Sea.
Trinidad.
We’ll begin our visit at the workshop of Chichi Santander, a prominent figure in traditional Trinitarian pottery, where we’ll get a closer look at this centuries-old craft. Then, we’ll take a walking tour of the historic center, considered an open-air museum and declared a World Heritage Site. As we stroll along its cobblestone streets, we’ll admire colonial architecture around the main square, visit the iconic Bar La Canchánchara, and explore the Santería Yemayá Temple, dedicated to the sea goddess. A santero will introduce us to the beliefs and rituals of this ancient Afro-Cuban religion. Lunch will be included at a charming local restaurant.
Departure from Trinidad toward the coast.
Arrival at Playa Ancón Resort. Check-in at Memories Trinidad del Mar Hotel (all-inclusive). Free afternoon to enjoy the Caribbean Sea at one of the island’s most beautiful beaches, unwind at the resort, or return on your own to Trinidad’s historic center.
Transfer to Trinidad. In the evening, we’ll offer a transfer to the center of Trinidad so you can soak up the city’s vibrant atmosphere, with live Cuban music near the cathedral and cozy local restaurants.
Return to the hotel.
We’ll travel through the rural heart of south-central Cuba, passing green sugar cane plantations, gentle hills, and small towns that still preserve the true essence of the Caribbean.
Departure from Trinidad. We’ll head into the heart of the historic Valley of the Sugar Mills, once the thriving center of Cuba’s sugar industry during the 18th and 19th centuries.
San Isidro de los Destiladeros, Valley of the Sugar Mills. We’ll visit this well-preserved former sugar mill, where we’ll delve into the history of sugar production, the region’s economic boom, and the crucial—yet tragic—role of slavery in this process.
Departure from San Isidro toward Manaca Iznaga.
Manaca Iznaga.
At this iconic plantation estate, you’ll have the opportunity to climb its historic watchtower, which offers a breathtaking 360° view of the valley. The tower, a powerful symbol of control and colonial wealth, stands as a reminder of an era shaped by forced labor and prosperity.
Departure from Manaca Iznaga. We’ll continue our journey northward.
Sancti Spíritus. This charming colonial town, often overlooked by tourists, welcomes us with its quiet and authentic atmosphere. We’ll stroll through its historic center, visit the main church and central square, and enjoy lunch included at a local restaurant.
Departure from Sancti Spíritus. We’ll cross the heart of Cuba heading east, passing grazing fields, palm groves, and rural villages.
Camagüey.
Arrival in a city known for its vibrant artistic spirit, maze-like plazas, and traditional clay jars called tinajones. We’ll settle into our hotel. In the evening, we recommend exploring Camagüey’s lively nightlife and enjoying dinner at a local restaurant with live Cuban music.
This journey offers an in-depth look at Cuba’s inland beauty—fertile valleys, historic ruins, sugar cane plantations, and colorful colonial cities wrapped in the tropical greenery of the island’s central region.
We´ll start the day exploring the fascinating historic center of Camagüey, a UNESCO World Heritage Site.
Get ready to discover its maze-like streets, its four main squares, and visit the studio of Martha Jiménez, a renowned Cuban sculptor. This walking tour is full of art, architecture, and history.
Departure from Camagüey.
We’ll head east, traveling through towns rich in history. Along the way, we’ll make a short stop in Guaimaro, a significant site where Cuba’s first constitutional assembly was held in 1869. It was here that the country’s independence and the abolition of slavery were proclaimed—an essential chapter in Cuban history.
Arrival in Bayamo.
This charming colonial city breathes the spirit of Cuba’s independence movement. We’ll enjoy an included lunch at the Royalton Bayamo Hotel restaurant. Afterwards, we’ll visit Plaza del Himno, the historic square where Cuba’s national anthem was sung for the first time, and then stop by the local chess academy, where young talents train in an inspiring setting.
Departure from Bayamo. We’ll continue our route toward the most charismatic city in eastern Cuba.
Arrival in Santiago de Cuba.
Cuba’s second-largest city and birthplace of the revolution, Santiago is known for its vibrant culture, musical traditions, and rebellious spirit. To end the day, we’ll visit the famous Casa de la Trova, a cultural hotspot and meeting place for Cuban music lovers, where we’ll enjoy live performances full of rhythm, passion, and soul.
Today’s journey takes us through eastern Cuba, passing agricultural plains, palm groves, and historic towns, with the Sierra Maestra mountains visible in the distance.
We’ll begin our panoramic tour of Santiago de Cuba, the country’s second most important city—vibrant, historic, and full of passion.
We’ll visit Revolution Square and make a stop at the solemn Santa Ifigenia Cemetery, a national monument where Cuban heroes such as José Martí, Fidel Castro, and other key figures in the nation´s history are laid to rest.
We’ll travel 20 km inland through green hills to reach the National Shrine of Our Lady of Charity of El Cobre, Cuba’s patron saint.
This sacred place is a powerful symbol of unity, hope, and resilience, and we’ll witness the deep devotion it inspires among the Cuban people.
Departure from El Cobre, heading toward the coast.
Arrival at Castillo del Morro (San Pedro de la Roca).
Perched on a rocky promontory at the entrance to the bay, this UNESCO World Heritage Site is an awe-inspiring fortress. We’ll explore its Piracy Museum and then enjoy an included lunch at El Morro Restaurant, offering breathtaking views of the sea.
Return to Santiago’s historic center, where we’ll enjoy a walking tour of the city’s main square, the cathedral, the old town hall, and the Diego Velázquez House, one of the oldest colonial buildings in the Americas.
Free time to explore the city at your own pace.
Breakfast. End of our services. T
Timings are from the operator's itinerary and may change on the day.
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Request extra hotel nights before or after the tour. These cost extra.
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Fly from your preferred Indian city. International flights are separate from the tour price.
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A little more discovery
Inspiration for your free time. Only visits listed in the day-by-day plan are included in the tour.
The massive, historic main square of Mexico City, surrounded by the Metropolitan Cathedral, National Palace, and government buildings. It's the beating heart of the city.
Free entry listed · check before visitingThe largest and oldest cathedral in Latin America, built over two centuries on top of Aztec ruins. Its grand facade and opulent interiors are a testament to colonial power.
Free entry listed · check before visitingThe iconic pink neo-Gothic church dominating the city skyline, a masterpiece of architectural beauty and spiritual significance.
Free entry listed · check before visitingThe bustling central square, perfect for people-watching, enjoying live music, and soaking in the city's atmosphere.
Free entry listed · check before visitingA quirky, chaotic, and utterly charming museum dedicated to antique Mexican toys. It's a nostalgic journey through generations of playthings, packed floor to ceiling.
Weekday afternoon
Allow plenty of time to explore every nook and cranny. Don't expect pristine displays; it's a treasure hunt.
An architectural marvel, this 'megalibrary' features cantilevered bookshelves soaring multiple stories high, creating a futuristic and awe-inspiring space. It's a haven for book lovers and design enthusiasts.
Morning on a weekday
Go inside and walk the elevated walkways for the best views. It's a working library, so be respectful of the quiet atmosphere.
A vibrant cultural complex with multiple intimate theaters, a bar, and a unique 'microteatro' concept where short plays are performed in tiny rooms for small audiences. It's an experimental and engaging arts hub.
Evening, check schedule online
Try the microteatro for a unique experience; plays are short and affordable. Many performances are in Spanish, but the experience is still immersive.
A quirky and often overlooked wax museum featuring Mexican historical figures, celebrities, and pop culture icons. It's a fun, nostalgic trip.
Afternoon
Go with an open mind and appreciate the artistry and kitsch.
The route
Numbered pins are where you sleep and match the stops above. Small dots are places the coach passes through. Lines join the stops point to point, not along the road.
Before you book
Prices, paperwork and practical questions. Find what matters to you.
The operator's hotel options. Your exact hotel is confirmed closer to departure.
Lafragua 7, Tabacalera, Cuauhtémoc, 06030
Av. Lázaro Cárdenas 450, Centro, 61600
Álvaro Obregón, 10. Colonia Centro, Pátzcuaro, Michoacán, 61600
Agustín Yáñez 2760, Arcos vallarta, 44130 Guadalajara, Jalisco, Mexico
From ₹3,67,078 per person for the tour itself (per person on triple, land only, excludes flights), and from ₹5,66,584 per person with flight from bengaluru, the airport transfer and travel insurance. An NxVoy consultant confirms the exact figure for your dates and rooms and sends you a quote reference.
16 days and 15 nights across Mexico, Cuba, mexico City to Santiago De Cuba.
12 departure dates are published, 4 with seats open; the next is 27 December 2026. Seats must be confirmed before you book flights. Published availability is not a seat hold.
Your written quote will state the deposit, balance due date, payment currency, taxes and any agency charges. Review these before paying. Wait for confirmed tour seats before buying separate flights.
This tour runs in January, February, March, September, October, November, December. Its peak season is September, October, December.
Indicative amounts in US dollars from NxVoy destination research.
General services: Travel by bus with English speaking guide, basic travel insurance, hotel and breakfast buffet. Includes arrival transfer City tour in: Mexico City, Patzcuaro, Guadalajara, Guanajuato, Puebla, Havana, Trinidad, Camaguey, Santiago de Cuba Flights from India, visa assistance, airport transfers and separate travel insurance can be requested in your NxVoy quote. They are additional unless expressly included in the confirmed price.
Hotel check-in is usually from 2pm. An early arrival does not guarantee access to your room. Ask your consultant about an extra night and confirm where to meet the group before you travel.
Excursions marked optional are paid for separately. Ask your NxVoy consultant which ones can be arranged in advance and which are booked with your guide.
Yes. Ask NxVoy about visa assistance, fees and application timelines for your passport. Visa approval is decided by the relevant authorities and is not guaranteed.
Confirm the current requirements for your passport before booking. Visa fees and assistance are quoted separately unless explicitly included.
-Children under 3 years: free of charge (some shows may not admit children).. -From 3-8 years: 60% of the price of the tour.. -From 9-15 years: these children are eligible for a discount of 10% on the value of the tour.. One adult per child.
Cancellation charges depend on the policy assigned to your tour and when you cancel. Non-refundable services can add costs. Ask NxVoy for the policy number, deadlines and all charges in writing before paying. A cancellation request needs operator confirmation; sending a message alone does not complete it.
Talk it through with a travel expert.
Payment & cancellation
Know the total, payment dates and cancellation charges for your exact trip. Keep your written quote and booking confirmation together.
Your written quote will state the deposit, balance due date, payment currency, taxes and any agency charges. Review these before paying. Wait for confirmed tour seats before buying separate flights.
Cancellation charges depend on the policy assigned to your tour and when you cancel. Non-refundable services can add costs. Ask NxVoy for the policy number, deadlines and all charges in writing before paying. A cancellation request needs operator confirmation; sending a message alone does not complete it.
Only listed services are included. International flights, visas and optional outings usually cost extra. Check your quote for transfers and other additions.
Basic assistance cover applies during the tour. Check its limits and arrange any additional cover you need. You remain responsible for passport and entry documents.
Unused services may qualify for a future-trip credit, subject to conditions and deductions. A cash refund is not automatic.
Ask for an itemised total covering your chosen tour, room type, flights and extras, including any applicable Indian taxes, agency charges and currency-conversion terms. Confirm the exact payment dates and cancellation policy before you commit.
Your quote should distinguish Europamundo's tour conditions from any additional agency terms. If two documents differ, ask us to resolve the difference in writing before paying.
A short guide to the operator's 2026–27 conditions, checked 1 October 2026. Ask NxVoy for the full conditions with your written quote before booking.
From your door, and back again
Need flights, visa assistance or airport transfers? Tell us where you are starting. We will bring the pieces together in one personalised quote.
Tour reference 3413 · Prices are per person in the currency shown. Tour-only prices exclude flights.